Accuracy & Precision in Clinical Chemistry Analyzers: Advanced Washin

Accuracy & Precision – Part 2 – Role of “Advanced Washing Protocol” & “Type of Probe / Mixer” to minimize carry over &/or cross over in fully auto clinical chemistry analyzer

As we have discussed in part 1 of this blog, more number of probes are required to increase the speed (throughput) of fully auto clinical chemistry analyzers.

Actually, it’s not number of probes (separate for reagent & sample) but “Advanced Washing Protocol” & “Type of Probe / Mixer”, which ensures reduction in carry-over &/or cross over. So, let’s talk about it.

• Advanced Washing Protocol – After each transfer of liquid (reagent / sample), probe will go for internal and external washing. Traditional probe washing station is having one fundamental mistake in design, fresh water to wash probe (externally) is coming from the bottom of probe washing station and contaminated waste water (after probe washing) is also going towards bottom of probe washing station. So, it’s a clear indication of cross contamination. Again pressure wash is not possible in traditional probe washing station for external probe washing. In new Advanced 360^O Washing Protocol, fresh water for probe external wash is coming from side walls (360^O) and contaminated waste water (after probe washing) is going towards bottom of probe washing station. So, there is no possibility of cross contamination. Again pressure wash is possible in advanced washing protocol because water flow will be from side walls towards bottom of probe washing station.

• Type of Probe / Mixer – Smooth surface of metal will reduce the possibility of liquid to stick on it. This simple principle helps to reduce carry-over. Mirror polishing of probe and teflon coating of mixer makes their surface very smooth to reduce carry-over of liquid (reagent / sample / water)

Beacon group of companies are offering full range of clinical chemistry analyzers having throughput of 100, 200, 400 and 800 tests / hour. These clinical chemistry analyzers are equipped by all advance features including “Advanced Washing Protocol” as well as “Mirror Polished Probes & Teflon Coated Mixer”.